Quick #introduction!
I'm a researcher working on problems to do with deep learning and proteins at Microsoft Research New England. You'll see me post about interesting papers, pictures of food, and whatever else I'm interested in at the moment.
A protein language model is able to generate diverse functional lysozymes from 5 different Pfam families + predict whether generated enzymes will be functional.
@thisismadani @nikhil_ai @fraser_lab @RichardSocher @benwkrause @mohrbp @CaimingXiong
RT @ml4proteins
Happening *tomorrow* at 4 pm ET!
Sign up on our website for Zoom links https://www.ml4proteinengineering.com/signup https://twitter.com/ml4proteins/status/1618993641346969601
RT @minjeejang
Thrilled to finally share my work at @VivianGradinaru lab at @Caltech - we developed a spatial transcriptomics approach to visualize and quantitatively analyze pooled systemic AAVs (capsids and cargos) in intact tissue across species. 1/n https://twitter.com/naturebiotech/status/1618653509083365376
Something something dark forest?!
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RT @latestinspace
Gliese 581c is an exoplanet just 20 light-years away that orbits in its star’s habitable zone.
In 2008, scientists decided to send a radio signal containing 501 messages that will reach the planet in 2029.
📸: Scott Richard
(Artist render)
https://twitter.com/latestinspace/status/1469362792692072451
RT @ml4proteins
Next Tuesday (1/31) @ 4 pm ET we'll have @ginaelnesr talk about SVD of sequences to visualize sequence/residue space!
Sign up at https://www.ml4proteinengineering.com to receive Zoom links in your inbox and add events to your calendar!
Large masked language models for genomes! And nicely curated benchmarks for them!
Hugo Dalla-Torre @sacdallago @LopezMarie05 @thomas_pierrot @instadeepai
These are the only good pens
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RT @Chris_Grosse
OK, you can only write with ONE type of pen for the rest of your life, which one are you picking? (ignoring the ink color) https://t.co/vHhvfYQXxv
https://twitter.com/Chris_Grosse/status/1618384965162635264
RT @thisismadani
ChatGPT for biology? Excited to share our work on LLMs for protein design out today @NatureBiotech
https://nature.com/articles/s41587-022-01618-2
+ Proud to publicly announce @ProfluentBio with a $9M seed round to tackle meaningful challenges in biology with AI. Join us!
Improve conditional generation from FoldingDiff by Inserting a layer that converts internal angles to atomic directions.
Zhangyang Gao, Cheng Tan, Stan Z. Li
Use the distance maps from AF to reweight the members of a structural ensemble for a disordered protein. Generate the members using MD or even by doing unconditional generation from FoldingDiff.
@FBrotzakis @mvendruscolo14
Great Sting concert
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RT @parismarx
lmao, what are the three words? wrong answers only
https://twitter.com/parismarx/status/1617220819675148289
RT @matteo_aldeghi
Our team working on ML for chemistry/drug discovery was unfortunately affected by the recent layoffs at Google.
I’m still very much interested in how new technologies can accelerate research in the life and natural sciences.
RT @beyonkz
I need everyone reporting on the devastating #lunarnewyear shooting to know a few things about #montereypark (thread)
Senior Researcher in BioML at Microsoft Research New England. He/him/他. 🇹🇼